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Elesclomol Induces Copper-Dependent Ferroptosis in Colorectal Cancer Cells via Degradation of ATP7A

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In the presence of an antioxidant molecule capable of donating an electron to NBT, the characteristic purple color of formazan diminishes, and this decrease can be monitored spectrophotometrically at 560 nm (Glin et al

The researchers administered either a combination of sildenafil 25mg and intranasal PT-141 7.5mg, sildenafil and placebo, or double placebo in a randomized cross-over design